Zofran

For the treatment of emesis in cancer patients receiving highly emetogenic chemotherapy. For patients receiving intravenous chemotherapy or radiation therapy who have not experienced adequate control with other available anti-emetics. For patients receiving intravenous chemotherapy or radiation therapy who experience intolerable side effects with other anti-emetics. For the treatment of emesis in patients receiving radiation therapy which consists of single fraction treatment to the abdominal cavity, hemi-body irradiation and total body irradiation. NOTE: The therapeutic value of Zofran more than 24 hours after the last dose of chemotherapy is unproven. LU Authorization Period: 1 year and hydrea. MEETING CALLED TO ORDER: Dr. John Wernert, acting Chairman, called the meeting of the Indiana MEETING Medicaid DUR Board to order and welcomed everyone. APPROVAL OF MINUTES: Dr. Wernert asked for approval of the minutes from the October meeting. His request was moved, seconded, and carried with a unanimous vote. REMARKS FROM THE CHAIR: Dr. Wernert stated that the DUR Board accepts the recommendations of the Therapeutics Committee with the understanding that all applicable agreements will be executed within the time frame defined by ACS and OMPP. If the manufacturer does not submit the signed agreement to ACS within the time frame, then their medications that would have been deemed preferred in accordance with the agreement will be moved to non-preferred status. OPENING COMMENTS: Mr. Marc Shirley advised the Board members that there should be no discussion of supplemental rebates during today's open session. THERAPEUTICS COMMITTEE LIAISON REPORT: Dr. Pinkesh Patel presented the Therapeutics Committee's recommendations from the November 2nd meeting. He stated that as always the three primary drivers behind those recommendations were clinical implications, drug costs, and total program costs. The TCommittee reviewed seven therapeutic classes and offered the recommendations listed below. The Board discussed and acted on each class individually. 1. CNS Agents Anti-emetic Agents Maintain ondansetron as preferred but add the following quantity limits: 10 orally disintegrating tablets per fill; 1 bottle of oral liquid per fill Move Zofran to non-preferred status with quantity limit of 10 orally disintegrating tablets per fill; 1 bottle of oral liquid per fill Narcotics Move Panlor DC, Panlor SS, and Zerlor to non-preferred status Move Dihydrocodeine APAP Caffeine to non-preferred status Cyclooxygenase 2 Inhibitors No changes recommended Narcotic Antitussive 1st generation Antihistamine Combinations. For individuals who are living with HIV AIDS and opiatedependent. For confidential info, contact OMNI at 310.676.9688. 9 2000 and dilantin.

Finally, kytril granisetron ; and zofran ondansteron ; are among the newest anti-nausea drugs and zometa. He occasionally sees members from other teams and offers educational programs for the sailors who double as medics on their boats!

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Zofran during pregnancy learning disabilities Add : : 28 author : mark n 4 comments i about to have a ressection done after years of dealing with crohn' s. Explanation of Table Headings . Drugs with Limits No Prior Authorization ; . Celebrex, Vioxx . Carisoprodol . Preven . Schedule II & III analgesics: . Stadol . `Triptans' for Migraines: Amerge; Maxalt; Zomig . Ultram . Viagra . Miralax . Drugs Requiring Prior Authorization . Lactulose Chronulac, Cephulac ; . Cancidas caspofungin acetate ; . Flolan epoprostenol na; prostayclin; PGI2; PGX ; . Ritalin Methylphenidate . Amphetamines . Lufyllin dyphylline ; . Growth hormones for children . Growth hormones for adults . Darvon, Darvocet N 5-HT3 Receptor Antagonists: Zofran ondansetron HCL Anzemet dolasetron mesylate Kytril ondansetron HCL ; . Enbrel etanercept ; . Regranex becaplermin ; 0.01% topical gel . Panretin Topical Gel 0.1% 9-cis-retinoic acid ; alitretinoin ; . Adagen Pegademase bovine ; . Cerezyme Imiglyceraze . INHALERS . Nasal Anti-inflammatory Inhalers . ORAL INHALERS . Orlistat Xenical ; . Oseltamivir phosphate Tamiflu7 ; . Zanamivir Relenza ; . Low Molecular Weight Heparins LMWH ; : dalteparin sodium Fragmin tinazajparin Na Innohep enoxaparin Na Lovenox ; . Zyban or Nicotine Replacement Therapy . Zyban . Proton Pump Inhibitors PPIs ; . Lovenox . Tracleer . Anakinra Kineret ; . Epoetin Alfa Epogen, Procrit ; , Darbepoetin Alfa Aranesp ; . Tryptans' 5-HT1 agonists ; . Modafinil Provigil ; . NSAIDS . COX-2 Inhibitors . ACTIQ . morphine long acting formulations . Duragesic 25mcg, 50mcg, 75mcg OxyContin . Methadone . Non Sedating Antihistamines, excepting loratadine formulations . Atypical Antipsychotics . Sedative-hypnotics tolterodine tartrate LA Detrol LA ; Manuals: Physician Services, Pharmacy Services Page 1 of 42. 13. Antibiotics: Start within 4 hours of admit to hospital if not initiated in Pre-Op OR: Time G Cefazolin Ancef ; 1 gm IVPH q6h x 4 doses OR x Last dose in OR at ; Cefazolin Ancef ; 1 gm IVPH q6h until drain s ; removed Last dose in OR at ; Vancomycin 500mg IVPB q8h x 3 doses OR x doses Last dose in OR at ; Vancomycin 500mg IVPB q8h until drain s ; removed Last dose in OR at ; Pharmacist to dose and monitor Vancomycin 14. Other Medications: No anticoagulants unless ordered by Dr. Schneider ex. Aspirin, Warfarin, Lovenox, Heparin, Toradol, etc. ; Diazepam Valium ; 5mg IV po q6hr prn muscle spasms G Carisprodol Soma ; 350mg po q6h prn muscle spasms G Ranitidine Zantac ; 50mg IV q8h. Change to 150mg po daily when tolerating po well G Docusate Sodium Colace ; 100mg po bid G Promethazine Phenergan ; 25mg po IV pr q6h prn nausea vomiting G Ondansetron Zofran ; 4mg IV q4h prn nausea vomiting G Morphine mg IV every as needed for severe pain. Max: G Meperidine Demerol ; mg IV every as needed for severe pain. Max: G Oxycodone Apap Percocet ; 5 325 mg 1-2 tabs po q3-4h prn pain max 12 tabs 24 hours ; G Hydrocodone Apap Norco ; 5 325 mg 1-2 tabs o q6h prn pain max 12 tabs 24 hours ; G Sliding Scale insulin and accucheks See insulin sliding scale standard order sheet Low Medium High G PCA See PCA standing order sheet If present, remove scopolamine patch in 72 hrs. If patient discharged home with patch, instruct patient to remove on day 3. Patient may use meds from home, if not available from pharmacy, or per patient's request. Physician Signature Date.

Use of zofran in pregnancy Through the takeda global research & development center, inc the company has a robust pipeline with compounds in development for diabetes, cardiovascular disease and other conditions. July 17, 2003, Meeting #2 Class review of Hepatitis C Medication Management - Pegylated Interferonalfa, Ribavirin Recommend placing a duration of therapy limit of 16 weeks on peg-interferon and ribavirin and require a genotype and qualitative HCV RNA serum assay for continuation of treatment. Those patients who have an EVR 2 log decrease in viral load at 12 weeks ; will be approved for continuation of treatment for an additional 32 weeks for viral genotype 1 or 4 for a total of 48 weeks. Proof of ; An EVR is not required for genotype 2 or 3, but will receive a total of 24 weeks of therapy based on documentation of genotype. In addition, Copegus is the preferred ribavirin in conjunction interferon, or peginterferon. #3 Class Review of 5-HT3 Antiemetic Agents to Treat Severe Nausea Vomiting Recommend placing quantity limits on the 5-HT3 antagonists and on Emend with the quantity limits based on the average quantity per treatment session, an average of four 4 ; sessions per month, and on available package size of each product. Requests for higher doses would require PA. Quantity limits are as follows: Zofran : 4mg and 8mg: 12 tablets per month 24mg: 4 tablets per month Liquid: 50ml month Injection: 4 vials 20ml 40mg and 8 vials 2ml 4mg ; Kytril: 1mg tablets: 8 tablets per month Liquid: 30ml month Injection: 8 vials 1mg 1ml Passed 9 to 0 Passed 9 to 0. The biggest and most successful retailers offer exceptional growth prospects for Novartis. To capitalize on that opportunity, Novartis Consumer Health is redesigning its sales force and creating customer teams dedicated to key accounts starting with WalMart Stores, Inc., the world's biggest retailer. Wal-Mart and its retailing peers are more sophisticated, and more demanding of their suppliers. Novartis customer teams meet that challenge by providing nimble, high-caliber service. By pooling efforts of business units and drawing on cross-functional capabilities, the Wal-Mart Customer Team is generating synergies, and additional sales. Building business across a broader front is expected to add more than USD 100 million in new revenue for 2005 pushing annual Novartis sales to Wal-Mart over USD 1 billion for the first time.

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The transplant team requests that no transplant patient smoke. Smoking is one of the most significant risk factors for post-transplant complications.

Analyses, which reported median age between 65 and 70 years, male predominance, thrombocytopenia, 8, 20 leukopenia, leukocytosis, 8 and organomegaly, 3, 8 respectively, in 22%, 10% to 25%, 18% to 30%, and 20% to 50% of patients. Fifty percent to 90% of patients had anemia.3, 8, 9 The median of mIgM ranged between 25 and 30 g L.8, 9 BenceJones proteinuria was found in only 36% of patients, probably because few patients had immunofixation. Cryoglobulinemia was present in 15% to 20% of patients, 3, 8 cold chronic hemolytic anemia and peripheral neuropathy in less than 10% of patients, 3, 8 and amyloidosis in less than 5% of patients.3, 8 Similarly, the overall survival of the training series agreed with the 60-month median survival times previously reported.1, 8, 9 Cause-specific survival has been considered an appropriate endpoint in WM because it controls for the many unrelated deaths among older patients.3 However the frequency of unrelated deaths should probably be taken into account for treatment decision and evaluation; therefore, we analyzed overall survival, as previously performed for other prognostic scoring systems established for chronic malignancies such as chronic granulocytic leukemia, 24 especially for malignancies occurring in the elderly, such as chronic lymphocytic leukemia, 11, 12 myelodysplastic syndromes, 25.

NON SELF-ADMINISTERED INJECTABLE DRUGS Drug Name WYCILLIN XYLOCAINE 1% XYLOCAINE 10% IM FOR CARDIAC XYLOCAINE W DEXTROSE YELLOW JACKET VENOM PROTEIN YELLOW-HORNET VENOM PROTEIN YF-VAX ZANTAC ZEMURON ZENAPAX ZEVALIN ZINACEF BAG ZINACEF VIAL ZINECARD ZITHROMAX ZOFRAN IN DEXTROSE ZOSTAVAX ZOSYN ZOSYN ZOVIRAX ZYPREXA Generic Name penicillin g procaine lidocaine 1% hcl lidocaine 10% hcl lidocaine 5% dextrose 7.5% yellow jacket venom protein yellow hornet venom protein yellow fever vaccine ranitidine hcl rocuronium bromide daclizumab ibritumomab tiuxetan cefuroxime sodium d5w cefuroxime sodium dexrazoxane azithromycin ondansetron hcl d5w zoster vaccine live piperacillin tazobactam piperacillin tazobactam dex-is acyclovir sodium olanzapine Drug Tier 5 Requirements Limits.

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